Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842096 | 1.00 | HSD11B1 (0.37) | HSD11B1HSD11B2KDM1ACYP19A1CNR1 | |
| SCHEMBL9841327 | 0.94 | KDM1A (0.37) | HSD11B1HSD11B2KDM1ACYP19A1STS | |
| SCHEMBL9841427 | 0.88 | KDM1A (0.39) | KDM1A | |
| SCHEMBL9841191 | 0.81 | KDM1A (0.41) | KDM1A | |
| SCHEMBL10585311 | 0.80 | CYP19A1 (0.51) | HSD11B1HSD11B2CYP19A1CNR1CNR2 | |
| SCHEMBL10584455 | 0.80 | MMP2 (0.46) | HSD11B1HSD11B2 | |
| SCHEMBL9841467 | 0.79 | SCN9A (0.37) | HSD11B1HSD11B2STS | |
| SCHEMBL9841568 | 0.79 | SCN9A (0.37) | HSD11B1HSD11B2STS | |
| SCHEMBL9841282 | 0.79 | SCN9A (0.37) | HSD11B1HSD11B2STS | |
| SCHEMBL9841587 | 0.79 | KDM1A (0.33) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |