Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.56 |
| ▸ | THRA | P10827 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | RARB | P10826 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841985 | 1.00 | THRB (0.56) | THRBTHRAMAPTSMN1; SMN2RARB | |
| Fluoride SCHEMBL9841949 | 1.00 | THRB (0.56) | THRBTHRAMAPTSMN1; SMN2RARB | |
| Fluoride SCHEMBL9841536 | 0.99 | THRB (0.56) | THRBTHRAMAPTSMN1; SMN2RARB | |
| Fluoride SCHEMBL9841387 | 0.94 | MAPT (0.51) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL9341873 | 0.92 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL9016853 | 0.92 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL8375690 | 0.92 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL9342490 | 0.92 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL8380722 | 0.92 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL8357893 | 0.92 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |