Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841550 | 0.94 | MEN1 (0.33) | MEN1KMT2ASLC6A4OPRM1CYP2C9 | |
| Fluoride SCHEMBL9841583 | 0.94 | MEN1 (0.33) | MEN1KMT2ASLC6A4OPRM1CYP2C9 | |
| Fluoride SCHEMBL9841621 | 0.91 | OPRM1 (0.31) | SLC6A4OPRM1SLC6A2 | |
| Fluoride SCHEMBL9842077 | 0.84 | — | — | |
| SCHEMBL9841692 | 0.79 | KDM1A (0.34) | MEN1KMT2ASLC6A4OPRM1 | |
| Fluoride SCHEMBL9841326 | 0.76 | STS (0.33) | SLC6A4OPRM1SLC6A2 | |
| SCHEMBL9841410 | 0.75 | KDM1A (0.33) | MEN1KMT2A | |
| SCHEMBL9841861 | 0.74 | KDM1A (0.33) | MEN1KMT2ACYP2C9CYP2C19NPSR1 | |
| SCHEMBL9841553 | 0.74 | KDM1A (0.33) | MEN1KMT2ACYP2C9CYP2C19NPSR1 | |
| SCHEMBL9841587 | 0.74 | KDM1A (0.33) | MEN1KMT2ACYP2C9CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |