Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841588 | 0.91 | MAPT (0.44) | ALDH1A1MAPTLMNAKMT2AGAA | |
| SCHEMBL9841677 | 0.89 | MAPT (0.43) | MAPTLMNAKMT2APRSS1NPC1 | |
| SCHEMBL9841437 | 0.88 | KMT2A (0.50) | ALDH1A1MAPTLMNAKMT2AHPGD | |
| SCHEMBL9841541 | 0.88 | MAPT (0.47) | ALDH1A1MAPTKMT2AMEN1PRSS1 | |
| SCHEMBL9841931 | 0.87 | PRSS1 (0.47) | ALDH1A1MAPTKMT2AMEN1PRSS1 | |
| SCHEMBL9841910 | 0.87 | PRSS1 (0.47) | ALDH1A1MAPTKMT2AMEN1PRSS1 | |
| SCHEMBL9841905 | 0.87 | PRSS1 (0.47) | ALDH1A1MAPTKMT2AMEN1PRSS1 | |
| SCHEMBL9841274 | 0.86 | MAPT (0.53) | TP53MAPTLMNAKMT2ATSHR | |
| SCHEMBL9842076 | 0.85 | RXRA (0.40) | RXRARXRBTP53ALDH1A1MAPT | |
| SCHEMBL9841548 | 0.84 | LMNA (0.55) | TP53MAPTLMNAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |