Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.81 |
| ▸ | DRD3 | P35462 | 11/20 | 0.66 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 5/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197530 | 1.00 | DRD2 (0.81) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL9197525 | 1.00 | DRD2 (0.81) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL9200670 | 0.90 | DRD2 (0.85) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL9199135 | 0.90 | DRD2 (1.00) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL9196530 | 0.88 | DRD2 (0.85) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL9196198 | 0.84 | DRD2 (0.78) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL9197591 | 0.83 | DRD2 (0.77) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL13415659 | 0.83 | DRD2 (0.77) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL9202507 | 0.83 | DRD2 (0.79) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL9202518 | 0.83 | DRD2 (0.79) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431580-A2 | Substituted cyclohexanols as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |