Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | CCNC | P24863 | 1/20 | 0.57 |
| ▸ | CDK8 | P49336 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905987 | 0.90 | KMT2A (0.73) | KMT2ACCNCCDK8LMNAPARP10 | |
| SCHEMBL2455357 | 0.90 | KMT2A (0.73) | KMT2ACCNCCDK8LMNAPARP10 | |
| Fluoride SCHEMBL9841468 | 0.88 | LMNA (0.63) | KMT2ALMNAMAPTNPC1PRSS1 | |
| Fluoride SCHEMBL9842106 | 0.88 | LMNA (0.56) | KMT2ALMNAMAPTTHRBNPC1 | |
| Fluoride SCHEMBL9841603 | 0.85 | TP53 (0.49) | KMT2ALMNAPARP10MAPTTHRB | |
| SCHEMBL11768997 | 0.85 | KMT2A (0.72) | KMT2ACCNCCDK8LMNAPARP10 | |
| SCHEMBL11943005 | 0.85 | KMT2A (0.68) | KMT2ACCNCCDK8LMNAPARP10 | |
| SCHEMBL12736338 | 0.85 | KMT2A (0.68) | KMT2ACCNCCDK8LMNAPARP10 | |
| Fluoride SCHEMBL9842043 | 0.84 | NPC1 (0.69) | KMT2ALMNAMAPTNPC1PRSS1 | |
| Fluoride SCHEMBL9841796 | 0.84 | NPC1 (0.69) | KMT2ALMNAMAPTNPC1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |