Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199916 | 0.89 | ALDH1A1 (0.57) | TP53RXRARXRBALDH1A1PRSS1 | |
| SCHEMBL12154217 | 0.89 | ALDH1A1 (0.57) | TP53RXRARXRBALDH1A1PRSS1 | |
| SCHEMBL12154283 | 0.89 | ALDH1A1 (0.57) | TP53RXRARXRBALDH1A1PRSS1 | |
| SCHEMBL26832415 | 0.89 | ALDH1A1 (0.57) | TP53RXRARXRBALDH1A1PRSS1 | |
| Fluoride SCHEMBL9841404 | 0.89 | MAPT (0.53) | TP53PRSS1KMT2AF2PRSS2 | |
| Fluoride SCHEMBL9841387 | 0.86 | MAPT (0.51) | PRSS1KMT2ARAB9AMAPTLMNA | |
| Fluoride SCHEMBL9841846 | 0.85 | KMT2A (0.62) | ALDH1A1PRSS1KMT2AMAPTLMNA | |
| Fluoride SCHEMBL9841536 | 0.85 | THRB (0.56) | ALDH1A1KMT2AMAPTLMNATHRB | |
| SCHEMBL11550359 | 0.84 | TP53 (0.59) | TP53RXRARXRBALDH1A1PRSS1 | |
| SCHEMBL12154284 | 0.84 | TP53 (0.59) | TP53RXRARXRBALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |