Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200867 | 0.84 | ALDH1A1 (0.46) | DRD2 | |
| SCHEMBL9200871 | 0.84 | ALDH1A1 (0.46) | DRD2 | |
| SCHEMBL9200874 | 0.84 | ALDH1A1 (0.46) | DRD2 | |
| SCHEMBL9199399 | 0.77 | GRIN2B (0.55) | DRD2 | |
| SCHEMBL9202985 | 0.72 | HRH3 (0.48) | — | |
| SCHEMBL9202990 | 0.72 | HRH3 (0.48) | — | |
| SCHEMBL9202976 | 0.72 | HRH3 (0.48) | — | |
| SCHEMBL9196218 | 0.71 | CCR1 (0.48) | — | |
| SCHEMBL9842132 | 0.71 | CCR1 (0.48) | — | |
| SCHEMBL9196219 | 0.71 | CCR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431580-A2 | Substituted cyclohexanols as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1991-06-12 | — | — | EP | claimed |