Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 12/20 | 0.43 |
| ▸ | ESR1 | P03372 | 12/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | UQCRB | P14927 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433146 | 0.80 | GSK3A (0.33) | — | |
| SCHEMBL16195430 | 0.75 | ESR1 (0.47) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL31013192 | 0.72 | ESR1 (0.39) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL15841589 | 0.70 | MEN1 (0.41) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL19882686 | 0.70 | ESR2 (0.56) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL24280271 | 0.69 | ESR1 (0.46) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL22335854 | 0.69 | ESR1 (0.80) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL18750 | 0.69 | ESR1 (0.80) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL4063477 | 0.69 | ESR1 (0.80) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL6761025 | 0.66 | ESR1 (0.76) | ESR2ESR1CYP3A4LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041516-A | Macromolecules | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-08-20 | — | — | US | disclosed |