SCHEMBL4063477

SCHEMBL4063477

CC(c1ccc(O)cc1)(c1ccc(O)cc1)c1ccc(C(C)(c2ccc(O)cc2)c2ccc(O)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.80
ESR2 Q92731 11/20 0.80
CYP3A4 P08684 4/20 0.68
LMNA P02545 2/20 0.68
TYR P14679 2/20 0.68
HPGD P15428 2/20 0.68
HSD17B10 Q99714 2/20 0.68
AR P10275 1/20 0.68
TSHR P16473 1/20 0.68
SLC6A2 P23975 1/20 0.68
SLC6A4 P31645 1/20 0.68
HTR6 P50406 1/20 0.68
ESRRG P62508 1/20 0.68
SLC6A3 Q01959 1/20 0.68
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
ALDH1A1 P00352 3/20 0.56
SHBG P04278 1/20 0.54
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22335854 1.00 ESR1 (0.80) ESR1ESR2CYP3A4LMNATYR
SCHEMBL18750 1.00 ESR1 (0.80) ESR1ESR2CYP3A4LMNATYR
SCHEMBL6761025 0.97 ESR1 (0.76) ESR1ESR2CYP3A4LMNATYR
SCHEMBL1456440 0.92 ESR1 (0.70) ESR1ESR2CYP3A4LMNATYR
SCHEMBL22336149 0.92 ESR1 (0.70) ESR1ESR2CYP3A4LMNATYR
SCHEMBL12004872 0.92 ESR1 (0.70) ESR1ESR2CYP3A4LMNATYR
SCHEMBL10772499 0.92 ESR1 (0.70) ESR1ESR2CYP3A4LMNATYR
SCHEMBL35973 0.92 ESR1 (0.84) ESR1ESR2CYP3A4LMNATYR
SCHEMBL9652258 0.92 LMNA (0.84) ESR1ESR2CYP3A4LMNATYR
SCHEMBL8373998 0.92 ESR1 (0.70) ESR1ESR2CYP3A4LMNATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4514334-A Polyphenolic compounds GENERAL ELECTRIC COMPANY (US) 1985-04-30 US claimed
US-11130724-B2 Compound, resin, composition, resist pattern formation method, and circuit pattern formation method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-09-28 US disclosed
US-7556902-B2 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2009-07-07 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-20060046169-A1 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2006-03-02 US disclosed
US-6919419-B2 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTRO-PHOTOGRAPHIC PHOTOCONDUCTOR, ELECTRO-PHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY LTD. (JP) 2005-07-19 US disclosed
US-6790571-B2 FORMED FROM N-(4-(2,2-BIS(4-HYDROXYPHENYL)VINYL)PHENYL)-N,N BIS(4-TOLYL)AMINE; IMPROVED DURABILITY; FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICE RICOH COMPANY, LTD. (JP) 2004-09-14 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20040002574-A1 Aromatic block polycarbonate resin, diphenol compound for preparation of the polycarbonate resin, electro-photographic photoconductor, electro-photographic image forming apparatus and process, and process cartridge RICOH COMPANY, LTD. (JP) 2004-01-01 US disclosed
US-6664361-B2 Aromatic polycarbonates; electrography RICOH COMPANY, LTD. (JP) 2003-12-16 US disclosed
US-5976746-A ELECTROCONDUCTIVE SUPPORT; PHOTOCONDUCTIVE LAYER RICOH COMPANY, LTD. (JP) 1999-11-02 US disclosed
EP-0600447-B1 Aromatic polycarbonate and production method thereof MITSUI CHEMICALS INC (JP) 1998-10-07 EP disclosed
US-5475079-A Nontoxic catalytic condensation polymerization yields pure polycarbonates free from discoloration DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-12-12 US disclosed
US-5468836-A Catalytic polymerization with ester interchange in nitrogen catalyst DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1995-11-21 US disclosed
US-5426170-A Interfacial polymerization of aromatic dihydroxy compound, carbonate precursor, alkali metal or alkaline metal base, water and solvent, endcapping MITSUI TOATSU CHEMICALS, INC. (JP) 1995-06-20 US disclosed
EP-0622418-A2 (Co)polycarbonate composition and process for preparing the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-02 EP disclosed
EP-0600447-A2 Aromatic polycarbonate and production method thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-06-08 EP disclosed
EP-0577849-A1 POLYCARBONATE AND PRODUCTION THEREOF DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1994-01-12 EP disclosed
US-4921923-A Ethers of oligomeric phenol-diketone condensation products and a vinyl-benzyl compound ALLIED SIGNAL INC. (US) 1990-05-01 US disclosed
US-4514334-A Polyphenolic compounds GENERAL ELECTRIC COMPANY (US) 1985-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11130724-B2 Compound, resin, composition, resist pattern formation method, and circuit pattern formation method RER1, NBAS, INTS9 ESR1 713/4885ESR2 1033/4885CYP3A4 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.