Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20845234 | 0.82 | SPHK1 (0.37) | SPHK1USP2SMN1; SMN2HCRTR2CHRM2 | |
| SCHEMBL8551293 | 0.81 | SPHK1 (0.34) | SPHK1USP2SMN1; SMN2HCRTR2CHRM2 | |
| SCHEMBL14750633 | 0.81 | SPHK1 (0.38) | SPHK1USP2SMN1; SMN2HCRTR2 | |
| SCHEMBL8554509 | 0.81 | SPHK1 (0.36) | SPHK1USP2SMN1; SMN2HCRTR2CHRM2 | |
| SCHEMBL5495814 | 0.80 | SPHK1 (0.35) | SPHK1HCRTR2 | |
| SCHEMBL8145278 | 0.80 | SPHK1 (0.35) | SPHK1HCRTR2 | |
| SCHEMBL8112146 | 0.80 | SPHK1 (0.35) | SPHK1HCRTR2 | |
| SCHEMBL8112149 | 0.80 | SPHK1 (0.35) | SPHK1HCRTR2 | |
| SCHEMBL17356198 | 0.78 | SPHK1 (0.35) | SPHK1USP2SMN1; SMN2HCRTR2CHRM2 | |
| SCHEMBL15157131 | 0.78 | SPHK1 (0.35) | SPHK1USP2SMN1; SMN2HCRTR2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454302-A2 | Tuftsin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |