Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 3/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842561 | 0.99 | RARB (0.39) | RARBRARARARGLTB4R2PTPN11 | |
| SCHEMBL9842752 | 0.97 | LTB4R2 (0.37) | RARBRARARARGLTB4R2MPL | |
| SCHEMBL9842443 | 0.92 | CYP2C9 (0.39) | RARBRARARARGLTB4R2MPL | |
| SCHEMBL9842361 | 0.87 | RARB (0.38) | RARBRARARARGLTB4R2MEN1 | |
| SCHEMBL9842351 | 0.85 | RARB (0.40) | RARBRARARARGLTB4R2PTPN11 | |
| SCHEMBL9842647 | 0.84 | PTPN11 (0.40) | RARBRARARARGLTB4R2PTPN11 | |
| SCHEMBL9842498 | 0.83 | PTPN11 (0.41) | RARBRARARARGLTB4R2PTPN11 | |
| SCHEMBL9842573 | 0.83 | RARB (0.40) | RARBRARARARGLTB4R2PTPN11 | |
| SCHEMBL9842441 | 0.81 | KDM4E (0.36) | LTB4R2LTB4RMEN1MAPTKMT2A | |
| SCHEMBL9842678 | 0.80 | RARA (0.35) | RARBRARALTB4R2PTPN11LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |