Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | RARA | P10276 | 3/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842647 | 0.97 | PTPN11 (0.40) | RARBRARALIPCLIPGPTPN11 | |
| SCHEMBL9842498 | 0.96 | PTPN11 (0.41) | RARBRARALIPCLIPGPTPN11 | |
| SCHEMBL9842678 | 0.94 | RARA (0.35) | RARBRARAPTPN11LTB4R2LTB4R | |
| SCHEMBL9842441 | 0.90 | KDM4E (0.36) | LTB4R2LTB4R | |
| SCHEMBL9842752 | 0.84 | LTB4R2 (0.37) | RARBRARALTB4R2LTB4RRARG | |
| SCHEMBL9842423 | 0.83 | RARB (0.38) | RARBRARAPTPN11LTB4R2LTB4R | |
| SCHEMBL9842561 | 0.82 | RARB (0.39) | RARBRARAPTPN11LTB4R2RARG | |
| SCHEMBL9842443 | 0.81 | CYP2C9 (0.39) | RARBRARALTB4R2LTB4RRARG | |
| SCHEMBL9842723 | 0.81 | TTR (0.44) | RARBRARALIPCLIPGLTB4R2 | |
| SCHEMBL9842253 | 0.78 | KDM4E (0.43) | RARBRARAPTPN11LTB4R2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |