SCHEMBL9842448

SCHEMBL9842448

CCC[C@H]1CC[C@H](OC(=O)c2ccc(-c3ccc(F)cc3F)cc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXTR P30559 1/20 0.41
AVPR1A P37288 1/20 0.41
KMT2A Q03164 1/20 0.40
SCN1A P35498 2/20 0.40
SCN2A Q99250 2/20 0.40
SCN3A Q9NY46 2/20 0.40
RARB P10826 1/20 0.40
CYP2C9 P11712 1/20 0.39
SERPINE1 P05121 1/20 0.39
KLKB1 P03952 2/20 0.39
ALDH1A1 P00352 2/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 2/20 0.38
PTGS2 P35354 1/20 0.38
HTR2A P28223 1/20 0.38
GRM2 Q14416 1/20 0.38
LMNA P02545 1/20 0.38
MAOB P27338 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9842802 0.93 RARB (0.43) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL9842724 0.92 RARB (0.45) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL9842645 0.91 RARB (0.47) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL9842399 0.91 OXTR (0.42) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL10922942 0.89 CYP2C9 (0.49) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL10924267 0.89 RARB (0.44) SCN1ASCN2ASCN3ARARBCYP2C9
SCHEMBL10922947 0.89 CYP2C9 (0.49) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL10922946 0.89 CYP2C9 (0.49) OXTRAVPR1AKMT2ASCN1ASCN2A
SCHEMBL10924264 0.89 RARB (0.44) SCN1ASCN2ASCN3ARARBCYP2C9
SCHEMBL11104527 0.88 SCN1A (0.48) KMT2ASCN1ASCN2ASCN3ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed