Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.42 |
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 3/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842456 | 0.87 | RARB (0.48) | PTPN11RARBRARAMCL1CAMKK1 | |
| SCHEMBL9842253 | 0.85 | KDM4E (0.43) | PTPN11RARBRARAMCL1CAMKK1 | |
| SCHEMBL9842723 | 0.84 | TTR (0.44) | RARBRARAMCL1CAMKK1CAMKK2 | |
| SCHEMBL9842584 | 0.82 | PTPN11 (0.57) | PTPN11RARBRARAMCL1 | |
| SCHEMBL9842467 | 0.82 | PTPN11 (0.57) | PTPN11RARBRARAMCL1 | |
| SCHEMBL9842489 | 0.81 | TTR (0.46) | RARBRARAMCL1CAMKK1CAMKK2 | |
| SCHEMBL9842401 | 0.81 | PTPN11 (0.55) | PTPN11RARBRARAMCL1PRKAB2 | |
| SCHEMBL9842652 | 0.77 | TTR (0.45) | RARBRARACAMKK1CAMKK2 | |
| SCHEMBL9842727 | 0.76 | TTR (0.46) | RARBRARACAMKK1CAMKK2 | |
| SCHEMBL9842537 | 0.75 | RARB (0.48) | PTPN11RARBRARAMCL1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |