Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | KDM4B | O94953 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.30 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245161 | 0.81 | NUDT1 (0.45) | HSP90AA1NUDT1BACE1PSMB5KDM4E | |
| SCHEMBL68884 | 0.79 | NUDT1 (0.44) | HSP90AA1NUDT1BACE1PSMB5KDM4E | |
| SCHEMBL14283748 | 0.79 | NUDT1 (0.44) | HSP90AA1NUDT1BACE1PSMB5KDM4E | |
| SCHEMBL1186506 | 0.79 | NUDT1 (0.44) | HSP90AA1NUDT1BACE1PSMB5KDM4E | |
| SCHEMBL1243046 | 0.79 | NUDT1 (0.42) | HSP90AA1NUDT1BACE1PSMB5KDM4E | |
| SCHEMBL10385924 | 0.77 | NUDT1 (0.41) | HSP90AA1NUDT1BACE1PSMB5KDM4E | |
| SCHEMBL9785309 | 0.75 | NUDT1 (0.44) | HSP90AA1NUDT1BACE1PSMB5KDM4E | |
| SCHEMBL27411644 | 0.75 | NUDT1 (0.39) | HSP90AA1NUDT1BACE1PSMB5KDM4E | |
| SCHEMBL27630258 | 0.75 | NUDT1 (0.41) | HSP90AA1NUDT1BACE1PSMB5KDM4E | |
| SCHEMBL18587581 | 0.75 | LMNA (0.42) | HSP90AA1NUDT1BACE1PSMB5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425682-A1 | BIS(CYCLOHEXYLPHENOL) COMPOUNDS AND THEIR USE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |