Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842737 | 0.88 | SMPD1 (0.45) | SMPD1GPR84FFAR1MAPTLCK | |
| SCHEMBL8460650 | 0.88 | SMPD1 (0.45) | SMPD1GPR84FFAR1MAPTLCK | |
| SCHEMBL28506896 | 0.86 | SMPD1 (0.42) | SMPD1GPR84FFAR1MAPTLCK | |
| SCHEMBL17824523 | 0.82 | SMPD1 (0.37) | SMPD1CA2 | |
| SCHEMBL4938749 | 0.81 | CA2 (0.40) | SMPD1GPR84CA2 | |
| SCHEMBL18550211 | 0.80 | — | — | |
| SCHEMBL29112774 | 0.80 | SMPD1 (0.40) | SMPD1GPR84FFAR1MAPTLCK | |
| SCHEMBL28326424 | 0.80 | GPR84 (0.52) | SMPD1GPR84FFAR1MAPTLCK | |
| SCHEMBL29060618 | 0.79 | ACE2 (0.34) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2137993 | 0.78 | GPR84 (0.44) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051465-A | Organopolysiloxane, silica and an organic peroxide which is hot air vulcanizable for moldings | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-09-24 | — | — | US | disclosed |