SCHEMBL9842547

SCHEMBL9842547

CCOC1(F)C=CC(c2ccccc2)C(F)=C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CACNA1D Q01668 4/20 0.33
HTR2A P28223 2/20 0.32
HTR2C P28335 2/20 0.32
HTR2B P41595 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9842625 0.89 HTR2A (0.30) HTR2AHTR2CHTR2B
SCHEMBL9842706 0.86 LTA4H (0.33)
SCHEMBL9842447 0.82 PPARG (0.34)
SCHEMBL8393880 0.81 CACNA1D (0.30) CACNA1D
SCHEMBL6677067 0.81 CACNA1D (0.38) CACNA1D
SCHEMBL11996405 0.79 KDM1A (0.33)
SCHEMBL11996455 0.76 MMP2 (0.32)
SCHEMBL9842466 0.71 MMP2 (0.31) HTR2AHTR2CHTR2B
SCHEMBL9842403 0.71 ELANE (0.33) HTR2AHTR2CHTR2B
SCHEMBL9842751 0.70 MMP2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed