Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195978 | 0.74 | ABCB1 (0.56) | ABCB1 | |
| SCHEMBL9274025 | 0.74 | ABCB1 (0.45) | ABCB1DRD2DRD3RXFP1 | |
| SCHEMBL25668662 | 0.74 | CYP3A4 (0.39) | ABCB1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL9681465 | 0.74 | ABCB1 (0.47) | ABCB1DRD2DRD3RXFP1 | |
| SCHEMBL9267040 | 0.73 | ABCB1 (0.45) | ABCB1DRD2DRD3RXFP1CNR1 | |
| SCHEMBL9274823 | 0.73 | ABCB1 (0.45) | ABCB1DRD2DRD3RXFP1CNR1 | |
| SCHEMBL9197921 | 0.70 | POLB (0.43) | ABCB1DRD2DRD3GPR6MAPT | |
| SCHEMBL9200212 | 0.66 | KDM4E (0.48) | ABCB1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL9681489 | 0.64 | ALDH1A1 (0.41) | ABCB1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL9356553 | 0.63 | ALDH1A1 (0.50) | MAPTKDM4EALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406656-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-01-09 | — | — | EP | disclosed |