Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | DHODH | Q02127 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820618 | 0.89 | HTT (0.66) | RAB9ANPC1HTTDHODHALDH1A1 | |
| SCHEMBL18640733 | 0.86 | HTT (0.63) | RAB9ANPC1HTTDHODHALDH1A1 | |
| SCHEMBL18640735 | 0.86 | HTT (0.63) | RAB9ANPC1HTTALDH1A1HPGD | |
| SCHEMBL8693733 | 0.83 | DHODH (0.57) | RAB9ANPC1HTTDHODHALDH1A1 | |
| SCHEMBL18640732 | 0.83 | HTT (0.76) | RAB9ANPC1HTTALDH1A1HPGD | |
| SCHEMBL8695054 | 0.82 | DHODH (0.50) | RAB9ANPC1HTTDHODHALDH1A1 | |
| SCHEMBL8569303 | 0.82 | DHODH (0.50) | RAB9ANPC1HTTDHODHALDH1A1 | |
| SCHEMBL8694084 | 0.81 | DHODH (0.76) | RAB9ANPC1HTTDHODHALDH1A1 | |
| SCHEMBL30648563 | 0.80 | RAB9A (0.88) | RAB9ANPC1HTTATMKMT2A | |
| SCHEMBL27332905 | 0.80 | HTT (0.53) | RAB9ANPC1HTTDHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434364-A2 | Benzodiazepine analogs for treating panic syndrome and for directly inducing analgesia | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |