Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696056 | 0.85 | RAB9A (0.52) | DHODHRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL8693815 | 0.84 | DHODH (0.52) | DHODHRAB9ANPC1HTTKMT2A | |
| SCHEMBL8696115 | 0.84 | DHODH (0.52) | DHODHRAB9ANPC1HTTKMT2A | |
| SCHEMBL29712338 | 0.84 | DHODH (0.64) | DHODHRAB9ANPC1HTTKMT2A | |
| SCHEMBL1375514 | 0.84 | DHODH (0.64) | DHODHRAB9ANPC1HTTKMT2A | |
| SCHEMBL9842635 | 0.83 | RAB9A (0.68) | DHODHRAB9ANPC1HTTKMT2A | |
| SCHEMBL8694084 | 0.83 | DHODH (0.76) | DHODHRAB9ANPC1HTTKMT2A | |
| SCHEMBL8691222 | 0.83 | L3MBTL1 (0.54) | DHODHRAB9ANPC1HTTKMT2A | |
| SCHEMBL8692652 | 0.83 | POLB (0.55) | RAB9ANPC1HTTKMT2AALDH1A1 | |
| SCHEMBL13483909 | 0.83 | KMT2A (0.61) | DHODHRAB9ANPC1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043993-C | Nonel naphthyridine derivatives and medical composition thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1999-07-07 | — | — | CN | disclosed |
| US-5817670-A | RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| CN-1156455-A | Nonel naphthyridine derivatives and medical composition thereof | YAMANOUCHI PHARMACUEITCAL CO L (JP) | 1997-08-06 | — | — | CN | disclosed |
| EP-0779292-A1 | NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |