Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842841 | 0.85 | PDE4A (0.49) | KMT2AADORA2BLMNAMAPTPDE4A | |
| SCHEMBL9842686 | 0.80 | ADORA2B (0.43) | ADORA2BLMNAPDE4AADORA2APDE4B | |
| SCHEMBL9842681 | 0.79 | PDE4A (0.62) | KMT2AADORA2BLMNAPDE4AADORA2A | |
| SCHEMBL9842692 | 0.78 | PDE4A (0.63) | KMT2AADORA2BLMNAMAPTPDE4A | |
| SCHEMBL9842831 | 0.76 | RXFP1 (0.67) | KMT2AADORA2BLMNAMAPTPDE4A | |
| SCHEMBL9842660 | 0.75 | RXFP1 (0.72) | KMT2AADORA2BLMNAMAPTPDE4A | |
| SCHEMBL27387998 | 0.74 | SMN1; SMN2 (0.71) | ADORA2BLMNARXFP1MAPK1SMN1; SMN2 | |
| SCHEMBL11057370 | 0.74 | PDE4A (0.48) | KMT2AADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL11058131 | 0.74 | PDE4A (0.62) | ADORA2BLMNAMAPTPDE4AADORA2A | |
| SCHEMBL9842640 | 0.72 | AKR1B1 (0.48) | ADORA2BLMNAPDE4AADORA2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430025-A2 | Xanthine compound, method for preparing thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |