SCHEMBL9842848

SCHEMBL9842848

CCCCCCCC1CCC(C(=O)O)(c2ccc(CCc3ccc(F)cc3)cc2F)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
RARB P10826 3/20 0.38
RARA P10276 1/20 0.38
RARG P13631 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C8 P10632 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
S1PR3 Q99500 1/20 0.38
PPARG P37231 4/20 0.35
PPARA Q07869 4/20 0.35
PLK1 P53350 1/20 0.35
PLK3 Q9H4B4 1/20 0.35
PPARD Q03181 1/20 0.35
PTGER1 P34995 1/20 0.34
PTGFR P43088 1/20 0.34
FAAH O00519 1/20 0.34
SPHK2 Q9NRA0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9843144 1.00 ITGB3 (0.39) ITGB3ITGA2BRARBRARARARG
SCHEMBL9842691 1.00 ITGB3 (0.39) ITGB3ITGA2BRARBRARARARG
SCHEMBL9842508 0.96 TP53 (0.36) ITGB3ITGA2BRARBRARARARG
SCHEMBL9842597 0.87 HDAC4 (0.36) CYP3A4CYP2C9CYP2C19
SCHEMBL9486874 0.86 CYP3A4 (0.35) ITGB3ITGA2BRARBRARARARG
SCHEMBL9842585 0.85 HDAC4 (0.41) RARBRARARARGPPARGPPARA
SCHEMBL9842600 0.85 HDAC4 (0.41) RARBRARARARGPPARGPPARA
SCHEMBL9842790 0.84 MEN1 (0.40) ITGB3ITGA2BRARBRARARARG
SCHEMBL9842432 0.84 MEN1 (0.40) ITGB3ITGA2BRARBRARARARG
SCHEMBL9486460 0.84 CYP3A4 (0.35) ITGB3ITGA2BRARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed