Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842790 | 1.00 | MEN1 (0.40) | MEN1KMT2AITGB3ITGA2BRARB | |
| SCHEMBL9842701 | 0.99 | MEN1 (0.40) | MEN1KMT2AITGB3ITGA2BRARB | |
| SCHEMBL9842223 | 0.96 | MEN1 (0.41) | MEN1KMT2AITGB3ITGA2BRARB | |
| SCHEMBL9843099 | 0.91 | MEN1 (0.38) | MEN1KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7508869 | 0.88 | AKR1C3 (0.43) | MEN1KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4827223 | 0.85 | MEN1 (0.47) | MEN1KMT2AITGB3ITGA2BRARB | |
| SCHEMBL9842691 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BRARBRARARARG | |
| SCHEMBL9842848 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BRARBRARARARG | |
| SCHEMBL9843144 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BRARBRARARARG | |
| SCHEMBL7507920 | 0.84 | AKR1C3 (0.44) | MEN1KMT2ACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |