Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.54 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842996 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9842866 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2GP6PPARG | |
| SCHEMBL1014 | 0.84 | GP6 (0.66) | AGTR1AGTR2GP6PPARG | |
| SCHEMBL9842853 | 0.82 | AGTR1 (0.52) | AGTR1AGTR2GP6PPARG | |
| SCHEMBL21083688 | 0.79 | GP6 (0.59) | AGTR1AGTR2GP6PPARG | |
| SCHEMBL9309634 | 0.78 | AGTR1 (0.52) | AGTR1AGTR2GP6PPARG | |
| SCHEMBL9311152 | 0.78 | AGTR1 (0.51) | AGTR1AGTR2GP6PPARG | |
| SCHEMBL9309628 | 0.78 | AGTR1 (0.56) | AGTR1AGTR2GP6 | |
| SCHEMBL21083964 | 0.77 | GP6 (0.56) | AGTR1AGTR2GP6PPARG | |
| SCHEMBL9309005 | 0.77 | AGTR1 (0.51) | AGTR1AGTR2GP6PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430709-A2 | Benzthiophen derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-05 | — | — | EP | disclosed |