Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843007 | 0.84 | LMNA (0.37) | LMNA | |
| Malonic Acid SCHEMBL9526167 | 0.82 | LMNA (0.48) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL9009065 | 0.79 | LMNA (0.50) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL9843156 | 0.77 | LMNA (0.56) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL9526337 | 0.77 | LMNA (0.51) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL9009198 | 0.76 | LMNA (0.49) | LMNASMN1; SMN2 | |
| SCHEMBL29962850 | 0.75 | LMNA (0.49) | LMNASMN1; SMN2CYP2C19HIF1A | |
| Malonic Acid SCHEMBL11132631 | 0.75 | LMNA (0.40) | LMNASMN1; SMN2 | |
| Malonic Acid SCHEMBL11130343 | 0.74 | LMNA (0.38) | LMNACYP2C19HIF1A | |
| SCHEMBL9284452 | 0.73 | LMNA (0.38) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004835-A | Substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides), process for their production as well as X-ray contrast media containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-02 | — | — | US | claimed |