SCHEMBL9843007

SCHEMBL9843007

Nc1c(I)c(C(=O)NC(CO)C(O)CO)c(I)c(C(=O)NC(CO)C(O)CO)c1I.Nc1c(I)c(C(=O)NC(CO)C(O)CO)c(I)c(C(=O)NC(CO)C(O)CO)c1I.O=C(O)C(O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL11130343 0.90 LMNA (0.38) LMNA
SCHEMBL9842902 0.84 LMNA (0.44) LMNA
SCHEMBL8074434 0.83 LMNA (0.35) LMNA
Malonic Acid SCHEMBL9761210 0.81 LMNA (0.45) LMNA
SCHEMBL7589586 0.76 LMNA (0.33) LMNA
SCHEMBL9843100 0.76 LMNA (0.52) LMNA
SCHEMBL9761063 0.76 LMNA (0.46) LMNA
SCHEMBL9009198 0.75 LMNA (0.49) LMNA
SCHEMBL9284452 0.75 LMNA (0.38) LMNA
SCHEMBL9544878 0.74 LMNA (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5004835-A Substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides), process for their production as well as X-ray contrast media containing them SCHERING AKTIENGESELLSCHAFT (DE) 1991-04-02 US disclosed