Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29038987 | 0.77 | CYP1A2 (0.49) | GRM2CYP1A2TSHRGAAKDM4E | |
| SCHEMBL7624975 | 0.76 | GRM2 (0.49) | GRM2TSHRGAAKDM4ENPSR1 | |
| SCHEMBL9842726 | 0.74 | TSHR (0.35) | GRM2CYP1A2TSHRGAAKDM4E | |
| SCHEMBL8550394 | 0.72 | TSHR (0.36) | GRM2CYP1A2TSHRGAAKDM4E | |
| SCHEMBL21899538 | 0.72 | TSHR (0.48) | GRM2TSHRGAAKDM4EALDH1A1 | |
| SCHEMBL8487069 | 0.72 | TRPA1 (0.52) | CYP1A2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL9226415 | 0.71 | CYP1A2 (0.57) | CYP1A2TSHRGAAKDM4ENPSR1 | |
| SCHEMBL8487337 | 0.71 | CYP2A6 (0.40) | TSHRGAAKDM4ENPSR1RXFP1 | |
| SCHEMBL9842740 | 0.70 | TSHR (0.34) | GRM2CYP1A2TSHRGAAKDM4E | |
| SCHEMBL29993589 | 0.69 | TSHR (0.50) | GRM2TSHRGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430709-A2 | Benzthiophen derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-05 | — | — | EP | disclosed |