Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.40 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.40 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.40 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331797 | 0.85 | SOAT1 (0.37) | POLMPOLKPOLLPOLHSOAT1 | |
| SCHEMBL8380025 | 0.85 | SOAT1 (0.37) | POLMPOLKPOLLPOLHSOAT1 | |
| SCHEMBL9574882 | 0.83 | SOAT1 (0.36) | POLMPOLKPOLLPOLHSOAT1 | |
| SCHEMBL10449057 | 0.81 | NR5A1 (0.40) | SOAT1MEN1KMT2ARECQLFAAH | |
| SCHEMBL21224653 | 0.81 | NR5A1 (0.40) | SOAT1MEN1KMT2ARECQLFAAH | |
| SCHEMBL28464418 | 0.81 | NR5A1 (0.40) | SOAT1MEN1KMT2ARECQLFAAH | |
| SCHEMBL10448680 | 0.80 | RARB (0.47) | — | |
| SCHEMBL28472097 | 0.78 | NR5A1 (0.37) | MEN1KMT2AKDM4ETDP1POLB | |
| SCHEMBL29154633 | 0.76 | SRR (0.31) | — | |
| SCHEMBL10445788 | 0.75 | POLM (0.32) | POLMPOLKPOLLPOLHSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413989-A2 | Liquid crystal compounds | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1991-02-27 | — | — | EP | disclosed |