Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 7/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 7/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 7/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | NOS2 | P35228 | 2/20 | 0.49 |
| ▸ | BRS3 | P32247 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9692690 | 0.99 | RAB9A (0.54) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 | |
| SCHEMBL9690543 | 0.85 | CYP2E1 (0.67) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 | |
| SCHEMBL9692929 | 0.84 | RAB9A (0.55) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 | |
| SCHEMBL9693023 | 0.81 | RAB9A (0.70) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 | |
| SCHEMBL25319204 | 0.81 | RAB9A (0.62) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 | |
| SCHEMBL9692587 | 0.80 | RAB9A (0.57) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 | |
| SCHEMBL9690499 | 0.80 | RAB9A (0.83) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 | |
| SCHEMBL9690585 | 0.80 | SMN1; SMN2 (0.75) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 | |
| SCHEMBL25321130 | 0.79 | RAB9A (0.62) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 | |
| SCHEMBL25319814 | 0.79 | RAB9A (0.64) | RAB9ANPC1PKMSMN1; SMN2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434405-A1 | Imidazo[4,5-c]pyridines as antiosteoporotic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-26 | — | — | EP | disclosed |