Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843054 | 1.00 | TBXAS1 (0.47) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9733100 | 0.84 | TBXAS1 (0.41) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9733096 | 0.84 | TBXAS1 (0.41) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9732639 | 0.79 | TBXAS1 (0.56) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9732636 | 0.79 | TBXAS1 (0.56) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL8527898 | 0.78 | TBXAS1 (0.39) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9733996 | 0.76 | TBXAS1 (0.48) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9734003 | 0.76 | TBXAS1 (0.48) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9733052 | 0.75 | TBXAS1 (0.47) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 | |
| SCHEMBL9732792 | 0.75 | TBXAS1 (0.47) | TBXAS1CHRNB2CHRNA4KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405391-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |