Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.36 |
| ▸ | APP | P05067 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842223 | 0.93 | MEN1 (0.41) | MEN1KMT2ATSHRAKR1C3AKR1C2 | |
| SCHEMBL9842701 | 0.92 | MEN1 (0.40) | MEN1KMT2ATSHRAKR1C3AKR1C2 | |
| SCHEMBL9842790 | 0.91 | MEN1 (0.40) | MEN1KMT2ATSHRAKR1C3AKR1C2 | |
| SCHEMBL9842432 | 0.91 | MEN1 (0.40) | MEN1KMT2ATSHRAKR1C3AKR1C2 | |
| SCHEMBL9842343 | 0.84 | TSHR (0.43) | MEN1KMT2ATSHRAKR1C3AKR1C2 | |
| SCHEMBL9842791 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2ATSHRAKR1C3AKR1C2 | |
| SCHEMBL2829785 | 0.82 | MEN1 (0.47) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL9842669 | 0.82 | MEN1 (0.46) | MEN1KMT2ATSHRAPPCYP3A4 | |
| SCHEMBL8563389 | 0.81 | MEN1 (0.45) | MEN1KMT2ATSHRAKR1C1APP | |
| SCHEMBL8678297 | 0.81 | AKR1C3 (0.43) | MEN1KMT2ATSHRAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |