SCHEMBL9843113

SCHEMBL9843113

Fc1ccc(C(Cn2cncn2)c2ccccc2F)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 8/20 0.58
MAPK1 P28482 1/20 0.44
HSP90AA1 P07900 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
LMNA P02545 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
ADRA1A P35348 1/20 0.39
CYP51A1 Q16850 1/20 0.39
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 2/20 0.38
CYP1A2 P05177 1/20 0.38
NPSR1 Q6W5P4 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6685818 0.85 CYP19A1 (0.50) CYP19A1MAPK1HSP90AA1CYP3A4CYP2C9
SCHEMBL10959984 0.77 CYP19A1 (0.56) CYP19A1HSP90AA1LMNAKMT2AALDH1A1
SCHEMBL11187781 0.77 MAPK1 (0.45) CYP19A1MAPK1HSP90AA1CYP3A4CYP2C9
SCHEMBL27775615 0.75 MAPK1 (0.43) CYP19A1MAPK1HSP90AA1CYP3A4CYP2C9
SCHEMBL27775612 0.74 CYP1A2 (0.42) CYP19A1MAPK1CYP3A4CYP2C9CYP2C19
SCHEMBL11273790 0.74 CYP19A1 (0.59) CYP19A1HSP90AA1CYP3A4CYP2C9CYP2C19
SCHEMBL9695247 0.74 CYP19A1 (0.59) CYP19A1MAPK1HSP90AA1CYP3A4CYP2C9
SCHEMBL11275601 0.74 CYP19A1 (0.59) CYP19A1MAPK1HSP90AA1CYP3A4CYP2C9
SCHEMBL10959736 0.73 KMT2A (0.57) CYP19A1HSP90AA1CYP3A4CYP2C19LMNA
SCHEMBL27602502 0.71 CYP19A1 (0.56) CYP19A1MAPK1HSP90AA1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007028753-A2 TRIAZOLE-BASED FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2007-03-15 WO disclosed
EP-0407854-A1 1-Halogen-vinylazoles and fungicides containing them BASF Aktiengesellschaft (DE) 1991-01-16 EP disclosed