Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028936 | 0.83 | CYP19A1 (0.44) | MAPK1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27956487 | 0.83 | CYP3A4 (0.47) | MAPK1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27402513 | 0.81 | GAA (0.45) | MAPK1CYP19A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11187781 | 0.79 | MAPK1 (0.45) | MAPK1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28054794 | 0.79 | CYP19A1 (0.49) | CYP19A1MEN1KMT2AALDH1A1HSP90AA1 | |
| SCHEMBL27775612 | 0.79 | CYP1A2 (0.42) | MAPK1CYP19A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27602502 | 0.77 | CYP19A1 (0.56) | MAPK1CYP19A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9843113 | 0.75 | CYP19A1 (0.58) | MAPK1CYP19A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27775796 | 0.74 | CYP11B1 (0.43) | CYP19A1CYP1A2CYP3A4CYP2D6POLB | |
| SCHEMBL27905535 | 0.72 | LMNA (0.43) | MAPK1CYP19A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101519402-B | Thiochromone compound, synthetic method thereof and application thereof in preparation of antifungal drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2010-12-29 | — | — | CN | disclosed |
| CN-101519402-A | Thiochromone compound, synthetic method thereof and application thereof in preparation of antifungal drugs | NANJING UNIVERSITY OF TECHNOLOGY | 2009-09-02 | — | — | CN | disclosed |