Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939703 | 0.79 | CREBBP (0.39) | DUSP3BACE1BACE2PLGPLAT | |
| SCHEMBL24119846 | 0.79 | BACE1 (0.39) | DUSP3BACE1BACE2PLGPLAT | |
| SCHEMBL9435785 | 0.77 | BACE1 (0.36) | DUSP3BACE1BACE2PLGPLAT | |
| SCHEMBL890390 | 0.75 | LMNA (0.46) | DUSP3BACE1BACE2PLGPLAT | |
| SCHEMBL159817 | 0.75 | LMNA (0.46) | DUSP3BACE1BACE2PLGPLAT | |
| Hydrochloric Acid SCHEMBL25415692 | 0.73 | LMNA (0.44) | DUSP3BACE1BACE2PLGPLAT | |
| SCHEMBL28063070 | 0.71 | BACE1 (0.36) | DUSP3BACE1BACE2PLGPLAT | |
| SCHEMBL28724041 | 0.71 | BACE1 (0.34) | BACE1BACE2PLGPLATLMNA | |
| SCHEMBL24939701 | 0.70 | LMNA (0.44) | DUSP3BACE1BACE2PLGPLAT | |
| SCHEMBL31236808 | 0.70 | DUSP3 (0.45) | DUSP3BACE1BACE2PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439354-A2 | Signal generating moiety and method for use | AMOCO CORPORATION (US) | 1991-07-31 | — | — | EP | disclosed |