Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887659 | 0.81 | GRIN2B (0.56) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9843115 | 0.73 | POLB (0.42) | POLBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11114919 | 0.71 | GRIN2B (0.50) | POLBGRIN1GRIN2B | |
| Mepiroxol SCHEMBL904581 | 0.63 | — | — | |
| SCHEMBL317676 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL11458780 | 0.62 | NAMPT (0.45) | POLBGPR84 | |
| Hydrochloric Acid SCHEMBL2123585 | 0.62 | GPR84 (0.49) | GPR84 | |
| Hydrochloric Acid SCHEMBL4093687 | 0.62 | GPR84 (0.49) | GPR84 | |
| SCHEMBL11114960 | 0.61 | POLB (0.48) | POLB | |
| SCHEMBL6179185 | 0.61 | AKR1B1 (0.54) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | claimed |
| EP-0418199-A2 | Guanidine derivatives | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | disclosed |