Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 12/20 | 0.41 |
| ▸ | TPH2 | Q8IWU9 | 12/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093687 | 0.76 | HPGD (0.54) | POLBSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL9298051 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7320101 | 0.74 | MEN1 (0.52) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9171903 | 0.72 | MAPT (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9842637 | 0.72 | MAPK1 (0.52) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL1822005 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9842711 | 0.71 | MEN1 (0.49) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9394689 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL10394883 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6885101 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430025-A2 | Xanthine compound, method for preparing thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-05 | — | — | EP | claimed |