Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL9843345 | 0.87 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9843156 | 0.87 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9526337 | 0.83 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9527194 | 0.78 | LMNA (0.66) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9527869 | 0.77 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9526167 | 0.77 | LMNA (0.48) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9530109 | 0.76 | LMNA (0.67) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL12885813 | 0.75 | LMNA (0.80) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL619944 | 0.75 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL12657374 | 0.74 | LMNA (0.56) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004835-A | Substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides), process for their production as well as X-ray contrast media containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-02 | — | — | US | claimed |