SCHEMBL619944

SCHEMBL619944

CC(=O)Nc1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.60
CYP2C19 P33261 1/20 0.60
HIF1A Q16665 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.49
EGFR P00533 1/20 0.39
SRC P12931 1/20 0.39
MAP2K1 Q02750 7/20 0.37
MAP2K2 P36507 2/20 0.34
PRKCZ Q05513 1/20 0.34
IARS2 Q9NSE4 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1557465 0.99 LMNA (0.59) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL14769256 0.97 LMNA (0.56) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL8378015 0.96 LMNA (0.56) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL9189596 0.96 LMNA (0.56) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL9237406 0.95 LMNA (0.55) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL8905505 0.95 SMN1; SMN2 (0.57) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL8905699 0.95 LMNA (0.55) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL622239 0.93 LMNA (0.54) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL10429709 0.93 LMNA (0.54) LMNACYP2C19HIF1ASMN1; SMN2EGFR
SCHEMBL30980824 0.93 LMNA (0.54) LMNACYP2C19HIF1ASMN1; SMN2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026101973-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-15 WO claimed
US-20260125517-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-07 US claimed
WO-2026090138-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 WO claimed
US-20260108635-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-23 US claimed
EP-4126814-B1 CONTINUOUS CRYSTALLISATION METHOD GE HEALTHCARE AS (NO) 2024-12-18 EP claimed
CN-118993927-A Synthesis method of 5-acetamido-2, 4, 6-triiodo-N, N' -bis (2, 3-dihydroxypropyl) -1, 3-benzenedicarboxamide 浙江海洲制药股份有限公司 2024-11-22 CN claimed
CN-115298162-B Continuous crystallization process 通用电气医疗集团股份有限公司 2024-11-08 CN claimed
CN-116421744-A Absorbable medical hydrogel and preparation method thereof 杭州融华再生医学科技有限公司 2023-07-14 CN claimed
US-20230133715-A1 CONTINUOUS CRYSTALLISATION METHOD GE HEALTHCARE AS (NO) 2023-05-04 US claimed
CN-115298162-A Continuous crystallization method 通用电气医疗集团股份有限公司 2022-11-04 CN claimed
EP-0925275-B1 PROCESS FOR IOHEXOL MANUFACTURE NYCOMED IMAGING AS (NO) 2001-12-12 EP claimed
US-5948940-A OXYALKYLATION OF5-ACETAMIDO-N,N-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODOPHTHAL IMIDE NYCOMED IMAGING AS (NO) 1999-09-07 US claimed
US-5847212-A Process for the preparation of iohexol ABBOTT LABORATORIES (US) 1998-12-08 US claimed
WO-1998013334-A1 PROCESS FOR THE PREPARATION OF IOHEXOL ABBOTT LABORATORIES (US) 1998-04-02 WO claimed
US-5705692-A Process for the preparation of iohexol ABBOTT LABORATORIES (US) 1998-01-06 US claimed
EP-0646021-B1 PURIFICATION OF CRUDE IOVERSOL USING CONTINUOUS DEIONIZATION MALLINCKRODT MEDICAL INC (US) 1996-11-27 EP claimed
EP-0646021-A1 PURIFICATION OF CRUDE IOVERSOL USING CONTINUOUS DEIONIZATION. MALLINCKRODT MEDICAL INC (US) 1995-04-05 EP claimed
EP-0646021-A4 PURIFICATION OF CRUDE IOVERSOL USING CONTINUOUS DEIONIZATION. MALLINCKRODT MEDICAL INC (US) 1994-10-07 EP claimed
US-5210300-A PURIFICATION OF CRUDE IOVERSOL USING CONTINUOUS DEIONIZATION MALINCKRODT MEDICAL, INC. (US) 1993-05-11 US claimed
WO-1993005820-A1 PURIFICATION OF CRUDE IOVERSOL USING CONTINUOUS DEIONIZATION MALLINCKRODT MEDICAL, INC. (US) 1993-04-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125517-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS MMP1, ILK, MMP13 LMNA 2390/4885CYP2C19 3586/4885HIF1A 1583/4885
US-20260108635-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BRDT, ILK, KLK3 LMNA 3855/4885CYP2C19 2180/4885HIF1A 1356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.