SCHEMBL9843545

SCHEMBL9843545

CS(=O)(=O)c1nnc(C(F)Cl)s1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA5A P35218 1/20 0.41
CA5B Q9Y2D0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10419730 0.86 CA1 (0.44) CA1CA2CA4CA5ACA5B
SCHEMBL9670579 0.84 CA1 (0.43) CA1CA2CA4CA5ACA5B
SCHEMBL11707048 0.78 CA2 (0.39) CA1CA2CA4CA5ACA5B
SCHEMBL20158613 0.78 CA1 (0.44) CA1CA2CA4CA5ACA5B
SCHEMBL11728922 0.76 CA1 (0.43) CA1CA2CA4CA5ACA5B
SCHEMBL9872420 0.73 CA2 (0.56) CA1CA2CA4CA5ACA5B
SCHEMBL9142464 0.72 CA2 (0.40) CA1CA2CA4CA5ACA5B
SCHEMBL8362436 0.69 CA1 (0.47) CA1CA2CA4CA5ACA5B
SCHEMBL9508988 0.69 CA1 (0.47) CA1CA2CA4CA5ACA5B
SCHEMBL9479930 0.68 CA1 (0.43) CA1CA2CA4CA5ACA5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443164-A1 Chlorofluoromethyl-thiadiazolyloxyacetic acidamide BAYER AG (DE) 1991-08-28 EP claimed
EP-0443164-A1 Chlorofluoromethyl-thiadiazolyloxyacetic acidamide BAYER AG (DE) 1991-08-28 EP disclosed