SCHEMBL9508988

SCHEMBL9508988

CS(=O)(=O)c1nnc(Cl)s1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA5A P35218 3/20 0.47
CA5B Q9Y2D0 3/20 0.47
CA4 P22748 2/20 0.47
FBP1 P09467 1/20 0.36
CA12 O43570 2/20 0.32
CA6 P23280 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
RAB9A P51151 1/20 0.30
CA3 P07451 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9872420 0.82 CA2 (0.56) CA1CA2CA5ACA5BCA4
SCHEMBL9736604 0.77 RXFP1 (0.36) CA1CA2CA5ACA5BCA4
SCHEMBL16432660 0.73 CA2 (0.48) CA1CA2CA5ACA5BCA4
SCHEMBL6824143 0.73 CA2 (0.48) CA1CA2CA5ACA5BCA4
SCHEMBL9359824 0.73 ALDH1A1 (0.50) CA1CA2CA5ACA5BCA4
SCHEMBL9681615 0.73 KDM4E (0.51) CA1CA2CA5ACA5BCA12
SCHEMBL10419730 0.73 CA1 (0.44) CA1CA2CA5ACA5BCA4
SCHEMBL6507990 0.71 CA2 (0.64) CA1CA2CA5ACA5BCA4
SCHEMBL3599000 0.71 CA1 (0.47) CA1CA2CA5ACA5BCA4
SCHEMBL8362436 0.71 CA1 (0.47) CA1CA2CA5ACA5BCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0348737-B1 HETEROARYLOXY-ACETIC ACID N-ISOPROPYL ANILIDES BAYER AG (DE) 1993-08-04 EP disclosed
EP-0505818-A1 Process for the preparation of 2-chloro-5-methylthio-1,3,4-thiadiazole BAYER AG (DE) 1992-09-30 EP disclosed
US-5096483-A Post- and preemergence; rice, soybeans, cereals, cotton, sugar beet BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US disclosed
US-5090991-A HERBICIDAL N-ISOPROPYLHETEROARYLOXYACETANILIDES BAYER AKATIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-4968342-A PRE-AND POSTEMERGENCE BAYER AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
EP-0348737-A1 Heteroaryloxy-acetic acid N-isopropyl anilides BAYER AG (DE) 1990-01-03 EP disclosed