Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.88 |
| ▸ | FAAH | O00519 | 5/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | CASP2 | P42575 | 1/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | SELP | P16109 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL340431 | 1.00 | DNM1 (0.88) | DNM1FAAHLPAR1NAAACASP2 | |
| SCHEMBL9565176 | 0.94 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL8660980 | 0.94 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL19281112 | 0.94 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL74418 | 0.94 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL8780431 | 0.94 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL3318222 | 0.94 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL15994307 | 0.94 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL5383341 | 0.94 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 | |
| SCHEMBL7924413 | 0.94 | DNM1 (1.00) | DNM1FAAHNAAACASP2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4976956-A | Water soluble and oil soluble quaternary ammonium compounds and amidoamine | HELENE CURTIS, INC. (US) | 1990-12-11 | — | — | US | claimed |
| EP-0410659-A2 | Method and composition to impart improved conditioning properties to the hair | HELENE CURTIS, INC. (US) | 1991-01-30 | — | — | EP | disclosed |
| US-4976956-A | Water soluble and oil soluble quaternary ammonium compounds and amidoamine | HELENE CURTIS, INC. (US) | 1990-12-11 | — | — | US | disclosed |