Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727281 | 0.73 | MEN1 (0.50) | S1PR5MAPTMEN1KMT2APOLB | |
| SCHEMBL187309 | 0.70 | MEN1 (0.50) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL4813515 | 0.65 | CHRM4 (0.58) | MEN1KMT2AHTR2C | |
| SCHEMBL27560417 | 0.63 | PTPN1 (0.59) | S1PR5MAPTMEN1KMT2AHTT | |
| SCHEMBL10622571 | 0.63 | HTR2C (0.44) | MAPTPARP10PARP11HTR2C | |
| SCHEMBL9585140 | 0.63 | HTR2C (0.51) | MAPTPARP10PARP11MEN1KMT2A | |
| SCHEMBL1263144 | 0.63 | TSHR (0.58) | HTR2CKIF11 | |
| SCHEMBL29678302 | 0.63 | TSHR (0.58) | HTR2CKIF11 | |
| SCHEMBL2379125 | 0.62 | CES2 (0.65) | POLBLMNA | |
| SCHEMBL31016229 | 0.62 | CES2 (0.65) | POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415030-A2 | 1-Substituted-1,2-dihydro-4-[(substituted)-phenyl]imidazo-[1,5-A]pyrimidine-8-carbonitriles | AMERICAN CYANAMID COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |