SCHEMBL31016229

SCHEMBL31016229

O=C(CCl)c1cccc(C(F)(F)F)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.65
CTNNB1 P35222 1/20 0.57
WNT3A P56704 1/20 0.57
ALDH1A1 P00352 3/20 0.56
POLB P06746 1/20 0.56
SRD5A2 P31213 1/20 0.54
YAP1 P46937 1/20 0.54
TEAD4 Q15561 1/20 0.54
TEAD2 Q15562 1/20 0.54
TRPA1 O75762 1/20 0.52
MAPK1 P28482 1/20 0.52
GSK3B P49841 1/20 0.52
HIF1A Q16665 1/20 0.52
ACHE P22303 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
P2RX1 P51575 1/20 0.51
LMNA P02545 1/20 0.51
HDAC3 O15379 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2379125 1.00 CES2 (0.65) CES2CTNNB1WNT3AALDH1A1POLB
SCHEMBL25348845 0.86 CES2 (0.61) CES2CTNNB1WNT3AALDH1A1POLB
SCHEMBL30758861 0.85 CES2 (0.69) CES2CTNNB1WNT3AALDH1A1POLB
SCHEMBL1712437 0.84 CES2 (0.67) CES2CTNNB1WNT3AALDH1A1POLB
SCHEMBL2073691 0.84 ACHE (0.72) CES2CTNNB1WNT3AALDH1A1POLB
SCHEMBL7376684 0.83 CES2 (0.57) CES2CTNNB1WNT3AALDH1A1POLB
SCHEMBL29393834 0.83 ALDH1A1 (0.55) CES2CTNNB1WNT3AALDH1A1POLB
SCHEMBL22556774 0.83 ALDH1A1 (0.55) CES2CTNNB1WNT3AALDH1A1POLB
SCHEMBL5660597 0.82 CES2 (0.56) CES2CTNNB1WNT3AALDH1A1POLB
SCHEMBL311526 0.82 CES2 (0.65) CES2CTNNB1WNT3AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118388332-A Preparation method of m-trifluoromethyl acetophenone 浙江予睿化学科技有限公司 2024-07-26 CN claimed