Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844285 | 0.88 | AGTR1 (0.46) | PPARGCYP19A1AGTR1AGTR2 | |
| SCHEMBL9843965 | 0.83 | CYP19A1 (0.46) | PPARGCYP19A1AGTR1AGTR2PDE4A | |
| SCHEMBL9844094 | 0.82 | PPARG (0.41) | PPARGCYP19A1AGTR1AGTR2 | |
| SCHEMBL9443092 | 0.80 | PPARG (0.68) | PPARGAGTR1AGTR2 | |
| SCHEMBL9843787 | 0.80 | PDE4A (0.44) | PPARGCYP19A1AGTR1AGTR2PDE4A | |
| SCHEMBL27771395 | 0.79 | AGTR1 (0.61) | PPARGCYP19A1AGTR1AGTR2 | |
| SCHEMBL27528971 | 0.78 | PPARG (0.55) | PPARGAGTR1AGTR2 | |
| SCHEMBL8070879 | 0.78 | AGTR1 (0.59) | PPARGAGTR1AGTR2 | |
| SCHEMBL8088552 | 0.78 | PPARG (0.46) | PPARGCYP19A1AGTR1AGTR2 | |
| SCHEMBL27771393 | 0.77 | AGTR1 (0.57) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407342-A2 | Pyrimidine derivatives | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | disclosed |