Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3460736 | 0.89 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL7177667 | 0.87 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL8076001 | 0.84 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL11092792 | 0.83 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL7326958 | 0.82 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9443092 | 0.82 | PPARG (0.68) | AGTR1AGTR2PPARG | |
| SCHEMBL9638129 | 0.82 | PPARG (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL9443042 | 0.81 | PPARG (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL7325291 | 0.80 | PPARG (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL9844285 | 0.80 | AGTR1 (0.46) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019048-A1 | USE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREPARATION OF DRUGS TO INCREASE THE SURVIVAL RATE OF RENAL TRANSPLANT PATIENTS | Merck Sharp Dohme (Italia) S.P.A. (IT) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999016437-A1 | USE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREPARATION OF DRUGS TO INCREASE THE SURVIVAL RATE OF RENAL TRANSPLANT PATIENTS | MERCK SHARP DOHME (ITALIA) S.P.A. (IT) | 1999-04-08 | — | — | WO | disclosed |