Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.60 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844227 | 0.94 | SIGMAR1 (0.59) | SIGMAR1HTR7TMEM97 | |
| SCHEMBL9844419 | 0.93 | SIGMAR1 (0.62) | SIGMAR1HTR7 | |
| SCHEMBL9844389 | 0.92 | SIGMAR1 (0.59) | SIGMAR1HTR7 | |
| SCHEMBL9678716 | 0.91 | SIGMAR1 (0.72) | SIGMAR1 | |
| SCHEMBL7292159 | 0.87 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL9844292 | 0.86 | SIGMAR1 (0.65) | SIGMAR1 | |
| SCHEMBL9844328 | 0.86 | OPRL1 (0.51) | SIGMAR1HTR7 | |
| SCHEMBL9844261 | 0.85 | SIGMAR1 (0.63) | SIGMAR1 | |
| SCHEMBL9844376 | 0.84 | SIGMAR1 (0.83) | SIGMAR1 | |
| SCHEMBL9844315 | 0.84 | SIGMAR1 (0.83) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |