Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678767 | 0.92 | SIGMAR1 (0.57) | OPRL1OPRM1SIGMAR1OPRK1 | |
| SCHEMBL9844227 | 0.88 | SIGMAR1 (0.59) | OPRM1SIGMAR1HTR7 | |
| SCHEMBL9844178 | 0.88 | SIGMAR1 (0.58) | OPRL1OPRM1OPRD1SIGMAR1 | |
| SCHEMBL9844284 | 0.86 | SIGMAR1 (0.54) | OPRL1OPRM1OPRD1SIGMAR1 | |
| SCHEMBL9844269 | 0.86 | SIGMAR1 (0.63) | SIGMAR1 | |
| SCHEMBL9844429 | 0.86 | OPRL1 (0.58) | OPRL1OPRM1OPRD1SIGMAR1ABCB11 | |
| SCHEMBL9844213 | 0.86 | SIGMAR1 (0.60) | SIGMAR1HTR7 | |
| SCHEMBL9844330 | 0.85 | OPRL1 (0.54) | OPRL1OPRM1OPRD1SIGMAR1ABCB11 | |
| SCHEMBL9844252 | 0.84 | SIGMAR1 (0.56) | OPRL1OPRM1OPRD1SIGMAR1ABCB11 | |
| SCHEMBL9844419 | 0.84 | SIGMAR1 (0.62) | SIGMAR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |