Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644668 | 0.73 | ALDH1A1 (0.44) | MAPTPOLBALDH1A1RECQLMMP8 | |
| SCHEMBL11270405 | 0.72 | EPHX1 (0.62) | MAPTPOLBALDH1A1EPHX1CYP3A4 | |
| SCHEMBL1134902 | 0.72 | EPHX1 (0.71) | MAPTPOLBALDH1A1EPHX1CYP3A4 | |
| SCHEMBL14455706 | 0.70 | CETP (0.60) | MAPTNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL11252135 | 0.70 | SMN1; SMN2 (0.40) | ALDH1A1RECQLMMP8CYP3A4CYP1A2 | |
| SCHEMBL16171037 | 0.69 | KDM4C (0.47) | MAPTNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL3077561 | 0.69 | HIF1A (0.57) | MAPTRECQLEPHX1CYP3A4CYP1A2 | |
| SCHEMBL8759 | 0.67 | SLC6A2 (0.56) | MAPTALDH1A1RECQLMMP8CYP3A4 | |
| SCHEMBL16171035 | 0.67 | KDM4C (0.45) | MAPTNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL2451040 | 0.66 | EPHX1 (0.75) | MAPTNPC1RAB9AALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |