SCHEMBL8759

SCHEMBL8759

CC(C)(Cc1ccccc1)C(N)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.56
TAAR1 Q96RJ0 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.55
HIF1A Q16665 1/20 0.55
MAPT P10636 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP3A4 P08684 2/20 0.49
CYP1A2 P05177 1/20 0.49
RECQL P46063 1/20 0.49
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
LMNA P02545 1/20 0.47
CYP2D6 P10635 1/20 0.47
RIPK1 Q13546 3/20 0.46
TRPA1 O75762 1/20 0.46
MMP8 P22894 3/20 0.45
BLM P54132 1/20 0.44
PLA2G10 O15496 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3136989 0.98 SLC6A2 (0.54) SLC6A2TAAR1SMN1; SMN2HIF1AMAPT
SCHEMBL24340783 0.87 SMN1; SMN2 (0.47) SLC6A2TAAR1SMN1; SMN2HIF1AMAPT
SCHEMBL27829250 0.85 SLC6A2 (0.54) SLC6A2TAAR1SMN1; SMN2HIF1AMAPT
SCHEMBL7785582 0.85 L3MBTL1 (0.54) SLC6A2TAAR1SMN1; SMN2HIF1AMAPT
SCHEMBL1147656 0.84 SLC6A2 (0.52) SLC6A2TAAR1SMN1; SMN2HIF1ACYP3A4
SCHEMBL517462 0.84 SMN1; SMN2 (0.57) SLC6A2TAAR1SMN1; SMN2HIF1ACYP3A4
SCHEMBL28869480 0.84 MAPT (0.51) SLC6A2MAPTKMT2ACYP3A4CYP1A2
SCHEMBL5268840 0.83 SLC6A2 (0.57) SLC6A2TAAR1SMN1; SMN2HIF1AMAPT
SCHEMBL407787 0.83 SLC6A2 (0.57) SLC6A2TAAR1SMN1; SMN2HIF1AMAPT
SCHEMBL1059557 0.83 SLC6A2 (0.52) SLC6A2TAAR1SMN1; SMN2HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017216726-A1 SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2017-12-21 WO claimed
US-8221733-B2 Acyclic or carbocyclic amines as antiseptics for bathroom fixtures LONZA AG (CH) 2012-07-17 US claimed
US-20100216890-A1 Disinfectant LONZA AG (CH) 2010-08-26 US claimed
US-20050277573-A1 Disinfectant LONZA AG (CH) 2005-12-15 US claimed
US-6939840-B2 Disinfectant LONZA AG (CH) 2005-09-06 US claimed
US-20050089496-A1 Virucidal disinfectant Arxada Switzerland AG (CH) 2005-04-28 US claimed
US-20040029767-A1 Disinfectant LONZA SOLUTIONS AG (CH) 2004-02-12 US claimed
US-5245004-A ANHYDROUS POLYMERIZATION OF CAPROLACTAM WITH CATALYST, COCATALYST AND ACTIVATOR UNITIKA LTD. (JP) 1993-09-14 US claimed
EP-0522533-A1 Process for polymerizing epsilon-caprolactam UNITIKA LTD. (JP) 1993-01-13 EP claimed
CN-115151550-B External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof 桑福德·伯纳姆·普雷比医学发现研究所 2024-11-22 CN disclosed
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 CN disclosed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN disclosed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN disclosed
WO-2024012554-A1 TPK AGONIST AND METHOD FOR TREATING NEURODEGENERATIVE DISEASES USING SAME 上海日馨医药科技股份有限公司 2024-01-18 WO disclosed
EP-0751927-A4 SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY CALIFORNIA INST OF TECHN (US) 1998-07-29 EP disclosed
CN-1142492-A Substituted N-(indole-2-carbonyl)-glycinamides and derivatives as antidiabetic agents PFIZER (US) 1997-02-12 CN disclosed
EP-0751927-A1 SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1997-01-08 EP disclosed
WO-1995025714-A1 SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1995-09-28 WO disclosed
US-5245004-A ANHYDROUS POLYMERIZATION OF CAPROLACTAM WITH CATALYST, COCATALYST AND ACTIVATOR UNITIKA LTD. (JP) 1993-09-14 US disclosed
EP-0522533-A1 Process for polymerizing epsilon-caprolactam UNITIKA LTD. (JP) 1993-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050089496-A1 Virucidal disinfectant O60361, GP6, PSMB6 SLC6A2 2258/4885TAAR1 165/4885SMN1; SMN2 2169/4885
US-20100216890-A1 Disinfectant SCN1B, ALDH7A1, SCNN1B SLC6A2 2601/4885TAAR1 249/4885SMN1; SMN2 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.